No.
As per SEBI minimum 50% margin has to come in cash and remaining 50% from collateral. Nothing changes for you as a Zerodha user as for overnight positions, we already block margins in 50:50 Cash - Collateral ratio.
You can check out more details on this here: 50:50 collateral rule to be more strictly enforced from now onwards? - #2 by MohammedFaisal